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Often, these companies will say that they are based in Canada, but in reality are based thousands of miles away in Africa or India. They are safest when you use them exactly as your doctor prescribes. The FDA urges those who experience hearing problems while on the drugs to stop taking the medications and call their doctor. In 2007, the Food and Drug Administration (FDA) announced labeling changes for PDE-5i medications so that the risk of hearing problems was more prominently displayed.
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In tests of 4-cylinder coupes, manual-transmission models averaged 22.7 to 30.6 mpg, automatic-transmission versions 25.2 mpg. Test manual-transmission 2WD returned 22 mpg, including gas-eating performance tests. Performance runs and high-speed freeways kept a California test car to 48.